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拉西地平
英文名称：Lacidipine
中文别名：(E)-4-[2-[3-(1,1-*)-3-氧代-1-基]]-1,4--2,6--3,5-二二
英文别名：3,5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-(3-(1,1-dimethylet
编码：103890-78-4
分子式：C26H33NO6
分子量：455.54
执行标准：BP2010
性状：白色或类白色结晶性粉末；在*中结晶，熔点173-176°C。
含量：≥99%
包    装：25KG硬纸板桶装，内衬两层聚乙烯薄膜。
贮    藏：远离火种、热源，密封储存，放至阴凉、干燥的环境，防潮。

Product Name:     Lacidipine   

Synonyms:     3,5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-(3-(1,1-dimethylet;diethylester,(e)-hoxy)-3-oxo-1-propenyl)phenyl);MOTENS;GX-1048;GR-43659X;CALDINE;(E)-4-[2-[3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL]PHENYL]-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER;LACIPIL   

:     103890-78-4   

MF:     C26H33NO6   

MW:     455.54   

Product Categories:     Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Calcium channel;Dihydropyridine   

Chemical Properties     White-to-Off-White Crystalline Solid   

Usage     A dihydropyridine calcium channel blocker. Antihypertensive   

Test Items Specification                                     Test Results
Appearance White or pale yellow crystalline powder        White crystalline powder
Solubility Practically insoluble in water ，freely soluble in acetone ，sparingly soluble in absolute ethanol  Conforms
Melting point About 178°                                            179°
Identification Meet the requirements                                  Conforms
Test Items Propan-2-ol Not more than 0.5%                   Conforms
Related Substances 
Impurity B Not more than 0.2%                                   Conforms
Other Single Impurity Not more than 0.2%                        Conforms
Total Impurity Not more than 0.5%                                  0.3%
Water             Not more than 0.2%                                  0.03%
Assay(on the dried basis)  Not less than 97.5% and not more than 102.0% 100.1%